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He saw through Stalin long before most of European intellectuals (such as Sartre) and his most famous novel (Darkness at Noon) did much to open people's eyes to the monster in the East. His campaign against capital punishment in England led to its eventual abolition, his articles in the Observer and his book Reflections on Hanging were hugely influential. Eventually he became disillusioned with politics and turned his attention to science. My favourite book of his is The Sleepwalkers, an accessible study of the history of cosmology that brought you into the worlds of Kepler, Galileo, Copernicus and Tycho Brae. A book I'm sure John Banville read before he started his novels on Kepler and Copernicus. I also enjoyed The Act of Creation, a study of the origins of creativity. Late in life he got into trouble with the Jewish lobby for having the temerity to suggest that the European Jews that emigrated to Palestine may have descended from the Khazars rather than from one of the 12 tribes of Israel. He also dabbled with parapsychology - an interest that did much to diminish his later reputation.
When his health deteriorated (he had Parkinson's amongst other ailments) he committed suicide along with his much younger (and healthier) wife Cynthia. He got much abuse for apparently dragging her into it but anyone reading of her long-term devotion to him would not have surprised at her willingness to join him.